Neurology -- Nakano et al. 56 (1): 87 Figure IG502432

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Figure 5. Extracellular signal-regulated kinase (ERK) and Elk-1 immunolocalization in control subjects. Positive deposits of (A) ERK and (B) Elk-1 in distal myopathy with rimmed vacuoles. (C) Small circular ERK-positive immunoreactivity in acid maltase deficiency. (D) ERK immunostaining in oculopharyngeal muscular dystrophy; only a small positive dot is observed in the vacuoles. (E) Cytoplasmic ERK-positive deposits in colchicine myopathy. (F) ERK-positive target formations in neurogenic muscular atrophy. (G) ERK and (H) Elk-1 in regenerating fibers in dermatomyositis. Elk-1 shows strong nuclear reactivity (x340 before reduction).