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Central nervous system chloromas preceding acute leukemia by one year

From the Section of Neurological Surgery, Baltimore Cancer Research Center, National Cancer Institute, National Institutes of Health, and the Department of Pathology, U.S. Public Health Service Hospital, Baltimore, Maryland

SUMMARYA case of central nervous system chloromas has been presented, along with the pathological and clinical manifestations of this tumor and its association with acute leukemia. This case is unique since it is the first reported case of intracranial chloromas preceding bone marrow evidence of acute leukemia by one year.

Dr. Walker's address is Section of Neurological Surgery, Baltimore Cancer Research Center, National Cancer Institute, 3100 Wyman Park Drive, Baltimore, Maryland 21211.

Submitted for publication Aug. 15, 1969; accepted Sept. 15, 1969.

The authors would like to thank Dr. Robert Schultz for helping with the evaluation of the pathological material and Dr. Stephen Hameroff for refemng the patient to our institution.