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NEUROLOGY 1975;25:1026
© 1975 American Academy of Neurology

Paroxysmal "nightmares"

Sequel of a stroke responsive to diphenylhydantoin

FRANCOIS BOLLER, M.D., DAVID G. WRIGHT, M.D., RALPH CAVALIERI, M.D., Ph.D. and HIROSHI MITSUMOTO, M.D.

Neurobehavior Unit, Cleveland Veterans Administration Hospital (Dr. Boller), and Neurology Service, University Hospitals of Cleveland and Case Western Reserve University School of Medicine (Drs. Boller, Wright, Cavalieri, and Mitsumoto), Cleveland, Ohio.

A 65-year-old man had nightmares a few weeks after a right temporal lobe infarction. Electroencephalography showed no epileptic activity. Therapy with diphenylhydantoin produced complete remission of his symptoms. On the bases of their acute onset, their association with sleep, their occasional occurrence while the patient was awake, the lack of effect of diazepam and flurazepam, and the good response to diphenylhydantoin, we propose that these episodes were partial seizures secondary to the right temporal lobe lesion.

Research supported in part by NIH Training Grant NSO 5087-18 from NINCDS and by funds from the Veterans Asministration Project No. 1017-05.

Received for publication March 10, 1975.

Reprint requests should be addressed to Dr. Boller, Neurobehavior Unit, Cleveland Veterans Administration Hospital, Cleveland, OH 44106.







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