Neurology
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Full Text (PDF)
Right arrow Correspondence:
Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when Correspondence are posted
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by STERN, L. Z.
Right arrow Articles by HANNAPEL, L. K.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by STERN, L. Z.
Right arrow Articles by HANNAPEL, L. K.
NEUROLOGY 1975;25:114
© 1975 American Academy of Neurology

Myopathy associated with linear scleroderma

A histochemical and electron microscopic study

LAWRENCE Z. STERN, M.D., CLAIRE M. PAYNE, Ph.D., JULIAN T. ALVAREZ, M.D. and LINDA K. HANNAPEL, A.B.

Departments of Neurology (Dr. Stern, Dr. Alvarez, Ms. Hannapel) and Pathology (Dr. Payne), The University of Arizona College of Medicine, Tucson.

Pathologic findings in biopsied rectus femoris muscle underlying an area of linear scleroderma are described. The affected muscle was weak and atrophic. On electromyography it showed motor unit potentials of decreased amplitude and duration. Light microscopic changes were minimal. There was atrophy of some histochemical type I fibers. More prominent changes were found at the ultrastructural level, where many of the capillary basal laminae were thickened and reduplicated. Most striking was the presence of two types of electron-dense, rounded inclusions within the mitochondria, one ranging from 29 to 47 nm in diameter and the other from 54 to 131 nm in diameter.

This study was supported in part by a grant from the Muscular Dystrophy Associations of America (to Dr. Stern and Dr. Raphael Gruener), by NIH grant NS 10417, and by a gift from Mr, and Mrs. Edward Watz.

Received for publication July 29, 1974.

Dr. Stern's address is Department of Neurology, University of Arizona Medical Center, Tucson, AZ 85724.




This article has been cited by other articles:


Home page
 Arch Pediatr Adolesc MedHome page
E. C. Moore, F. Cohen, Z. Farooki, and C.-H. Chang
Focal Scleroderma and Severe Cardiomyopathy: Patient Report and Brief Review
Arch Pediatr Adolesc Med, February 1, 1991; 145(2): 229 - 231.
[Abstract] [PDF]

Home page
 ANN INTERN MEDHome page
V. FALANGA, T. A. MEDSGER Jr., M. REICHLIN, and G. P. RODNAN
Linear Scleroderma: Clinical Spectrum, Prognosis, and Laboratory Abnormalities
Ann Intern Med, June 1, 1986; 104(6): 849 - 857.
[Abstract] [PDF]

Home page
 Arch DermatolHome page
High Titers of Antibodies to Single-Stranded DNA in Linear Scleroderma: Vincent Falanga, MD; Thomas A. Medsger, MD; Morris Reichlin, MD
Arch Dermatol, March 1, 1985; 121(3): 345 - 347.
[Abstract] [PDF]

Home page
 Arch DermatolHome page
J. A. Doyle, S. M. Connolly, and R. K. Winkelmann
Cutaneous and Subcutaneous Inflammatory Sclerosis Syndromes
Arch Dermatol, November 1, 1982; 118(11): 886 - 890.
[Abstract] [PDF]

Home page
 Arch NeurolHome page
R. A. Schwartz, A. S. Tedesco, L. Z. Stern, A. M. Kaminska, J. M. Haraldsen, and D. A. Grekin
Myopathy Associated With Sclerodermal Facial Hemiatrophy
Arch Neurol, September 1, 1981; 38(9): 592 - 594.
[Abstract] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 1975 by AAN Enterprises, Inc.