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NEUROLOGY 1975;25:150
© 1975 American Academy of Neurology

Autonomic dysfunction in botulism B

A clinical report

GERHARD JENZER, M.D., MARCO MUMENTHALER, M.D., HANS PETER LUDIN, M.D. and FRÉDÉRIC ROBERT, M.D.

Department of Neurology, Medical School of the University of Berne, Berne, Switzerland.

Nine cases of botulism B with preponderant effects upon cholinergic autonomic innervation are presented. Blurred vision and dry mouth were constant symptoms. Impairment of salivary and lacrimal secretion were detectable for months. In the absence of clinical signs, electromyographic studies did not reveal neuromuscular involvement. Administration of antitoxin in the late course of such cases is not recommended, but guanidine can be used. Doubt is cast upon a new clinical entity called "acute autonomic neuropathy."

Received for publication July 31, 1974.

Dr. Jenzer's address is Neurological Clinic, University of Bern, Inselspital, 3008 Bern, Switzerland.




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