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Isolation of herpes simplex virus from the cerebrospinal fluid in viral meningitis

Division of Infectious Diseases, Department of Medicine, Washington University School of Medicine, and the Diagnostic Laboratories of Barnes Hospital, St. Louis, Missouri.

Two cases of meningitis are reported in which the etiologic diagnosis was established by isolation of herpes simplex virus from the cerebrospinal fluid. Both patients were afebrile and had bradycardia when the cultures were obtained, and one patient had been thought to have leukemic meningitis. This experience added to that of others in the literature indicates the value of culture for herpes simplex virus in the cerebrospinal fluid.

Received for publication August 26, 1974.

Requests for reprints should be addressed to Dr. Harford at Washington University School of Medicine, Box 8051, 660 South Euclid Avenue, St. Louis, MO 63110.

This article has been cited by other articles:

				R. E. Morrison, S. A. Shatsky, G. E. Holmes, F. H. Top Jr, and A. N. Martins Herpes Simplex Virus Type I From a Patient With Radiculoneuropathy JAMA, January 26, 1979; 241(4): 393 - 394. [Abstract] [PDF]

				D. S. Minckler, E. B. McLean, C. M. Shaw, and A. Hendrickson Herpesvirus hominis Encephalitis and Retinitis Arch Ophthalmol, January 1, 1976; 94(1): 89 - 95. [Abstract] [PDF]