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NEUROLOGY 1975;25:267
© 1975 American Academy of Neurology

Downbeat nystagmus as a sign of brainstem involvement in acute meningoencephalitis

NATSUE SHIMIZU, M.D., JESSE WEINBERGER, M.D. and MELVIN D. YAHR, M.D.

Department of Neurology, The Mount Sinai School of Medicine of the City University of New York, New York City.

Two cases of acute meningoencephalitis, presumably viral in origin, with brainstem involvement are reported. Common to both patients during the course of their illness was coma, downbeat nystagmus, and ataxia. Although both reached what appeared to be a terminal state, recovery began following treatment with corticosteroids. The significance of the neurologic signs, particularly the unusual occurrence of downbeat nystagmus, is discussed, as is the appropriate management of the disorder.

This study was supported in part by NIH grant 5 T01 NS 05072.

Received for publication October 4, 1974.

Reprint requests should be addressed to Dr. Yahr, Department of Neurology, The Mount Sinai School of Medicine, 100th Street and Fifth Avenue, New York, NY 10029.







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