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NEUROLOGY 1975;25:430
© 1975 American Academy of Neurology

Epidemiologic study of migraine symptoms in young women

ROBERT E. MARKUSH, M.D., M.P.H., HERBERT R. KARP, M.D., ALBERT HEYMAN, M.D. and WILLIAM M. O'FALLON, Ph.D.

Center for Epidemiologic Studies, National Institute of Mental Health, Health Services and Mental Health Administration (Dr. Markush); Division of Neurology, Emory University School of Medicine, Atlanta, Georgia (Dr. Karp); and Duke University Medical Center, Durham, North Carolina (Drs. Heyman and O'Fallon).

Information about headache was collected from a nonclinical sample of 451 women, aged 15 to 44, in 12 major U.S. cities. Questions were asked in regard to the presence in the past year of headache, and of the following characteristic symptoms of migraine: unilateral location, throbbing quality, visual aura, vomiting, and severity sufficient to affect daily activities. Twenty-three percent of the women had headaches with two or more of these characteristics. The frequency of such symptoms was significantly greater in women who smoked or formerly had smoked cigarettes, in women with lower incomes and poor education, and in women with a history of hypertension, stomach ulcer, fainting, and a variety of emotional complaints. The frequency of reported symptoms of migraine did not vary significantly according to age, race, marital status, use of oral contraceptives, or number of living children. These findings do not support the commonly held clinical impression that migraine is uncommon among blacks or among the poorly educated.

This investigation was supported by a contract (NIH69–2250) from the National Institute of Child Health and Human Development, NIH, and the National Institute of Mental Health, HSMHA.

Received for publication August 6, 1974.

Reprint requests should be addressed to Dr. Markush at 1321 Geranium Street, N.W., Washington, DC 20012.




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