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Cervical myelopathy complicating cerebral angiography

Report of a case and review of the literature

Department of Neurology (Drs. Ramirez-Lassepas and Snyder) and the Department of Radiology (Drs. McClelland and Marsh), University of Minnesota, St. Paul-Ramsey Hospital, St. Paul, Minnesota.

Transverse cervical myelopathy, at C-6 level, followed injection of Renografin-60 into the right thyrocervical trunk during cerebral angiography. Review of the literature yielded only two cases in which attempted posterior fossa angiography resulted in cervical myelopathy. Two more cases were found. In one, cervical myelopathy occurred during aortography in a patient with coarctation of the aorta, and in the other it followed mediastinal angiography. Summation of anoxia, hemorrhage, and cellular toxicity is responsible for spinal cord necrosis following arterial injection of contrast material.

Dr. Ramirez-Lassepas' address is Department of Neurology, University of Minnesota, St. Paul-Ramsey Hospital, St. Paul, MN.

Accepted for publication October 8, 1976