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Aphasia Research Center and Neurology Department, Boston University School of Medicine; the Psychology Service, Boston VA Hospital (Dr. Stuss); the Department of Neurology, Boston VA Hospital, Boston University School of Medicine, and Braintree Hospital, Braintree, Massachusetts (Dr. Alexander); the Department of Neurology, Boston VA Hospital (Dr. Lieberman); and the Department of Radiology, Boston VA Hospital, Tufts University School of Medicine, Boston, Massachusetts (Dr. Levine).
We describe five patients with spontaneous, persistent confabulation. While the basis of confabulation in general is not known, the evidence in this specific group of patients with spectacular, impulsive, and spontaneous confabulation suggests a marked deficit in frontal function, superimposed upon a basic defect in memory, as a possible mechanism.
Reprint requests should be addressed to Dr. M.P. Alexander, BVAH, 150 S. Huntington Ave., Boston, MA 02130.
Dr. Stuss's address is Psychology Service, Boston VA Hospital, I50 S. Huntington Avenue, Boston, MA 02130.
Supported in part by NIH Grant No. NS 06209. Dr. Stuss was financed by the National Research Council of Canada and the Ontario Mental Health Foundation.
Accepted for publication May 2, 1978.
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