| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
|
|
|
|||||||
|
|||||||||
Department of Neurology, University of Minnesota School of Medicine, and the Departments of Neurology, Hennepin County Medical Center and St. Paul-Ramsey Medical Center, Minneapolis, MN.
Large doses of phenytoin were administered on 159 occasions to 139 adult patients. Most patients had had more than three seizures or were in status epilepticus. Based on response to treatment, patients could be divided into two groups. Those with excellent response (recurrent seizures, 10%; mortality, 1%) included known epileptics with exacerbation of seizures (n = 79, atypical alcohol withdrawal (61, or miscellaneous conditions (17). Those with poor results (recurrent seizures, 57%; mortality, 38%) included patients with anoxic or metabolic encephalopathy (14), stroke or other vascular disease (14), brain tumor (5), or trauma (5).
Address reprint requests to Dr. Cranford, Department of Neurology, Hennepin County Medical Center, 701 Park Ave. So., Minneapolis, MN 55415.
This study was supported by NINCDS Contract No. N01-NS-5-2327.
This paper was presented at the thirtieth annual meeting of the American Academy of Neurology, Los Angeles, April 1978.
Accepted for publication April 17, 1979.
This article has been cited by other articles:
|
|
 |
|
  P. D. Meek, S. N. Davis, D. M. Collins, B. E. Gidal, P. A. Rutecki, A. H. Burstein, J. H. Fischer, I. E. Leppik, R. E. Ramsay, and for the Panel on Nonemergency Use of Parenteral Ph Guidelines for Nonemergency Use of Parenteral Phenytoin Products: Proceedings of an Expert Panel Consensus Process Arch Intern Med, December 13, 1999; 159(22): 2639 - 2644. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 D. M. Treiman, P. D. Meyers, N. Y. Walton, J. F. Collins, C. Colling, A. J. Rowan, A. Handforth, E. Faught, V. P. Calabrese, B. M. Uthman, et al. A Comparison of Four Treatments for Generalized Convulsive Status Epilepticus N. Engl. J. Med., September 17, 1998; 339(12): 792 - 798. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 J. M. Pellock Status Epilepticus in Children: Update and Review J Child Neurol, October 1, 1994; 9(2_suppl): 2S27 - 2S35. [Abstract] [PDF]
|
|
|
|
 |
|
 Working Group on Status Epilepticus Treatment of Convulsive Status Epilepticus: Recommendations of the Epilepsy Foundation of America's Working Group on Status Epilepticus JAMA, August 18, 1993; 270(7): 854 - 859. [Abstract] [PDF]
|
|
|
|
 |
|
 J. D. Tobias, D. K. Baker, and C. A. Hurwitz Removal of Phenytoin by Plasmapheresis in a Patient with Thrombotic Thrombocytopenia Purpura Clinical Pediatrics, February 1, 1992; 31(2): 105 - 108. [Abstract] [PDF]
|
|
|
|
 |
|
 D. R. Abernethy and D. J. Greenblatt Phenytoin Disposition in Obesity: Determination of Loading Dose Arch Neurol, May 1, 1985; 42(5): 468 - 471. [Abstract] [PDF]
|
|
|
|
|
|
M. P. Earnest, J. A. Marx, and L. R. Drury Complications of Intravenous Phenytoin for Acute Treatment of Seizures: Recommendations for Usage JAMA, February 11, 1983; 249(6): 762 - 765. [Abstract] [PDF]
|
|
|
|
|
|
R. P. Simon, A. M. Lewis, and J. M. Bronstein Cardiovascular Response to Rapid Phenytoin Infusion During Seizures in Paralyzed Rats Arch Neurol, June 1, 1982; 39(6): 372 - 373. [Abstract] [PDF]
|
|
|
|
|
|
J. C. Cloyd, R. J. Gumnit, and L. W. McLain Jr Status Epilepticus: The Role of Intravenous Phenytoin JAMA, September 26, 1980; 244(13): 1479 - 1481. [Abstract] [PDF]
|
|
| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
