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Institute of Neurology and National Hospitals for Nervous Diseases, London, England.
The clinical and angiographic correlations of small deep infarcts seen on computed tomography (CT) scan were studied in 297 consecutive patients. Some of these showed the features described by Fisher1 as part of the lacunar syndrome. In a large number, a source of emboli from either a cardiac or a carotid source was highly probable; in a smaller number, other vascular diseases were present. The finding of a small deep infarct on CT does not exclude the need for further investigation of a possible embolic source in selected patients.
Address correspondence and reprint requests to Dr. Pullicino, Institute of Neurology and National Hospitals for Nervous Diseases, Queen Square, London WC1N 3BG, England.
Accepted for publication December 11, 1979.
Dr. Pullicino is supported by a grant from EMI Medical Ltd. and Dr. Nelson by the Ontario Heart Foundation.
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