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NEUROLOGY 1980;30:1292
© 1980 American Academy of Neurology

Neurologic prognosis after cardiopulmonary arrest

III. Seizure activity

Bruce D. Snyder, M.D., W. Allen Hauser, M.D., Ruth B. Loewenson, Ph.D., Ilo E. Leppik, M.D., Manuel Ramirez-Lassepas, M.D. and Robert J. Gumnit, M.D.

From the Department of Neurology (Drs. Snyder, Hauser, Leppik, Ramirez-Lassepas, and Gumnit), St. Paul-Ramsey Hospital and the University of Minnesota School of Medicine, and the Department of Neurology (Dr. Loewenson), University of Minnesota, Minneapolis, MN.

Nineteen (30%) of 63 adult survivors of cardiopulmonary arrest had seizures after admission to the hospital. Eleven of 19 had more than one type of seizure. Myoclonic seizures began within 12 hours of the arrest in eight patients, and after 3 or more days in four patients. Only two (17%) patients with myoclonic seizures survived. Partial seizures usually began within 12 hours of the arrest and were controllable with anticonvulsants; 4 of 12 patients survived. Two of four patients with generalized tonic-clonic seizures survived; one of four with "shivering" lived. Overall, patients with seizures had a survival rate of 32% (6 of 19), compared with 43% for patients without seizures. None of the survivors had recurrent seizures within 6 months after hospital admission.

Address correspondence and reprint requests to Dr. Snyder, Department of Neurology, St. Paul-Ramsey Medical Center, St. Paul, MN 55101.

Accepted for publication January 23, 1980.

This work was supported by the St. Paul-Ramsey Medical Education and Research Foundation, Grant No. 8117, and the Comprehensive Epilepsy Program, Grant No. NIH NSO-3364.




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