Neurology
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Full Text (PDF)
Right arrow Correspondence:
Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when Correspondence are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Keesey, J.
Right arrow Articles by Peter, J. B.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Keesey, J.
Right arrow Articles by Peter, J. B.
NEUROLOGY 1980;30:233
© 1980 American Academy of Neurology

Detection of thymoma in myasthenia gravis

John Keesey, M.D., Marshall Bein, M.D., Jerrold Mink, M.D., Frederick Sample, M.D., Dennis Sarti, M.D., Donald Mulder, M.D., Christian Herrmann, Jr., M.D. and James B. Peter, M. D., Ph.D.

Departments of Neurology (Drs. Keesey and Herrmann), Radiology (Drs. Rein, Mink. Sample, and Sarti) and Surgery (Dr. Mulder), UCLA School of Medicine, Los Angeles, and the Clinical Immunology Laboratories, Inc. (Dr. Peter). Santa Monica, CA.

Twenty patients with myasthenia gravis had chest radiography, conventional tomography, and computed tomography (CT) of the thorax within 1 month of thymectomy. Four of the six macroscopic tumors were detected on routine chest radiography; conventional tomography provided no additional information. CT detected all six macroscopic tumors and provided additional information that was not available by other procedures. However, 18 patients (90%) had anterior mediastinum densities on CT, which could not be distinguished preoperatively from thymic tumors. All six patients with macroscopic tumors had serum antistriational muscle antibody titers; this test was negative in 10 of 11 patients (91%) without thymoma. Chest radiography, CT of the thorax, and antistriational antibodies are the tests recommended for detection of a thymoma in patients with myasthenia gravis.

Address correspondence and reprint requests to Dr. Keesey, Reed Neurological Research Center, 710 Westwood Plaza, Los Angeles, CA 90024.

Accepted for publication August 10, 1979.

Portions of this paper were presented at the annual meeting of the American Academy of Neurology, Los Angeles, April 1978






HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 1980 by AAN Enterprises, Inc.