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NEUROLOGY 1980;30:487
© 1980 American Academy of Neurology

Cerebral embolism in Libman-Sacks endocarditis

Irwin S. Fox, M.D, Alexander M. Spence, M.D, Roger F. Wheelis, M.D and Louis A. Healey, M.D.

Department of Pathology (Neuropathology) (Drs. Fox and Spence), University of Washington School of Medicine, and the Mason Clinic (Drs. Wheelis and Healey), Seattle, WA.

Left homonymous hemianopia, hemiparesis, left-body clonic seizures, and progressive deterioration of consciousness complicated the clinical course of a 57-year-old woman with systemic lupus erythematosus (SLE). Autopsy documented the presence of multiple brain infarcts and cerebral arterial emboli that originated from the verrucae of Libman-Sacks endocarditis. Clinicians and pathologists should consider this unusual vascular mechanism of cerebral injury in patients with SLE who develop strokes.

Address correspondence and reprint requests to Dr. Spence, Neurology RG-20, University of Washington, Seattle, WA 98195.

Accepted for publication August 22, 1979.




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