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Long-term prognosis after carotid artery occlusion

From the Departments of Neurology and Diagnostic Radiology, Mayo Clinic and Mayo Foundation, Rochester, MN.

One hundred thirty eight patients with angiographi-cally proved carotid artery occlusion and minimal or no neurologic deficit were followed up for an average of 5 years. For patients 35 years old or over, the observed 5-year survival rate on an actuarial basis was 77% compared with an expected rate of 85% in a matched normal population. For patients 35 years old or over, the subsequent stroke rate was 3% per year, and two-thirds of the strokes were ipsilateral to the carotid artery occlusion. The observed stroke rate for all patients 35 years old or over was eight times the expected rate for a matched normal population. The relative risk of stroke was much greater in the younger patients with atherosclerotic carotid artery occlusion than in the older patients.

Address correspondence and reprint requests to Dr. Whisnant, Department of Neurology, Mayo Clinic, 200 First Street SW, Rochester, MN 55901.

Accepted for publication December 10, 1979.

This investigation was supported in part by Research Grant No. NS-6663 from the National Institutes of Health, Public Health Service.

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