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From the Departments of Medicine, Divisions of Neurology (Dr. Roeltgen) and Radiology (Dr. Weimer), the Milton S. Hershey Medical Center, Hershey, PA, and the Department of Neurology (Dr. Patterson), Harrisburg Hospital, Harrisburg, PA.
We studied the delayed neurologic complications of left atrial myxoma in 2 patients and analyzed 47 previously published cases. Embolic cerebral infarctions may occur before surgical removal of the primary cardiac tumor, but aneurysm formation and hemorrhage may be delayed, whether or not there is evidence of neurologic disorder at the time of initial surgery. The true incidence of these delayed complications is unknown. Resultant aneurysms may show progressive enlargement, and treatment with doxorubicin failed to prevent aneurysm enlargement in one patient. Better guidelines are needed for clinical management in these patients.
Address correspondence and reprint requests to Dr. Roeltgen, Department of Medicine, Division of Neurology, The Milton S. Hershey Medical Center, Hershey, PA 17033.
This paper was presented at the thirty-first annual meeting of the American Academy of Neurology, Chicago, IL, April 1979.
Accepted for publication April 3, 1980
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