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Acute myelopathy caused by fibrocartilaginous emboli

Departments of Pathology (Dr Bots! and Neurology (Drs. Wattendorff and Endtzi, Municipal Hospitals of The Hague, and the Departments of Neuropathology (Dr. Bots) and Neurology (Drs. Buruma and Roos), University of Leiden, The Netherlands.

Fibrocartilaginous embolism of the spinal cord has been reported in only 17 cases. We describe three new cases, all seen within a year, of infarction of the spinal cord by fibrocartilaginous emboli in the ramifications of the anterior spinal artery. These emboli probably originate from degenerated intervertebral disks, but full understanding of the pathogenesis is still lacking. The disease has been found more frequently in dogs. Because the pathologist is not likely to attempt to demonstrate the condition unless the clinician has proposed the diagnosis, the true frequency will be known only when the clinical picture is widely recognized.

Address correspondence and reprint requests to Dr. Endtz, Department of Neurology, Municipal Hospitals, Leyweg 275, 2545 CH, The Hague, The Netherlands.

Accepted for publicatlon February 11. 1981.

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