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Hypersomnia associated with alveolar hypoventilation in myotonic dystrophy

Marshfield Clinic and Marshfield Medical Foundation, Marshfield, WI.

Myotonic dystrophy was recently discovered in a 38-year-old man complaining of excessive daytime sleep for 18 years. Pulmonary function tests showed alveolar hypoventilation resulting from defective central respiratory control. Polysomnography revealed a low sleep apneic index insufficient to account for the hypersomnia. Sleep cycles were normal, without REM excess or REM onset. A similar membrane abnormality in muscle and brainstem neurons could account for the myotonia, hypersomnia, and alveolar hypoventilation.

Address correspondence and reprint requests to Dr. Hansotia, Marshfield Clinic and Marshfield Medical Foundation, Marshfield, WI 54449.

Accepted for publication February 4, 1981.

Presented at the American EEG Society meeting in Boston, MA, September 7, 1980.

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