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Recovery from drug-induced alpha coma

Department of Neurology. Japan Red Cross Medical Center. Tokyo. Japan

A 41-year-old man in deep coma after drug over-dosage showed electroencephalographic activity of alpha frequency. He remained comatose for 20 hours, and assisted ventilation was required for 28 hours, but he eventually recovered Alpha coma has generally been considered to have grave prognostic implications, but acute drug intoxication is an exception to this rule. Intensive supportive therapy is important.

Address correspondence and reprint requests to Dr. Kuroiwa, Department of Neurology, Institute of Brain Research, Faculty of Medicine, University of Tokyo. 7-3-1, Hongo. Bunkyo-ku, Tokyo, 113. Japan.

Accepted for publication January 6, 1981.