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Departments of Neurology, Uniformed Services University of the Health Sciences (Dr. Pleet) and National Naval Medical Center (Drs. Pleet and Vengrow), Bethesda, MD, and Duke University Medical Center (Dr. Massey), Durham, NC.
Address correspondence and reprint requests to Capt. Pleet, M.C., U.S.N., Chairman, Department of Neurology, Uniformed Services University of the Health Sciences, Bethesda, MD 20014.
Congenital bicuspid aortic valve, one of the most common congenital heart abnormalities, may become infected, may calcify, and may cause progressive stenosis or progressive insufficiency. While no previous reports suggested cerebral emboli in the absence of valvular infection, we studied four such cases. In all, cerebral angiography was normal and no extracardiac source of emboli was demonstrated. Microthrombus formation and valvular thickening with incompetence could eventuate in embolization.
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