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Visual evoked potentials in sarcoidosis

Department of Neurology (Drs. Streletz, Chambers, and Bae) and the Department of Medicine (Dr. Israel), Jefferson Medical College of Thomas Jefferson University, Philadelphia, PA.

Address correspondence and reprint requests to Dr. Streletz, Department of Neurology Jefferson Medical College 1025 Walnut Street, Philadelphia, PA 19107.

The visual evoked potential to pattern reversal was recorded in 50 patients with sarcoidosis. Abnormalities of latency and amplitude were found in 15 patients (30%), including all 4 patients with clinically evident brain disease and 4 of 17 patients with overt ocular disease. Twenty-nine patients had no clinical evidence of ocular or neurologic disease, and 7 of them (24%) had abnormalities of the VEP, implying subclinical sarcoid lesions in structures at the base of the brain.

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