Neurology
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Full Text (PDF)
Right arrow Correspondence:
Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when Correspondence are posted
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Etienne, P.
Right arrow Articles by Collier, B.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Etienne, P.
Right arrow Articles by Collier, B.
NEUROLOGY 1981;31:1552
© 1981 American Academy of Neurology

Alzheimer disease

Lack of effect of lecithin treatment for 3 months

Pierre Etienne, M.D., Dolly Dastoor, M.A., Serge Gauthier, M.D., Robin Ludwick, M.A. and Brian Collier, Ph.D.

Douglas Hospital Research Center (Dr Etienne, Ms Dastoor, and Ms Ludwick), the Montreal Neurological Institute (Dr Gauthier), and the Department of Pharmacology and Therapeutics (Dr Collier), McGill University Montreal, Quebec, Canada

Address correspondence and reprint requests to Dr Etienne Douglas Hospital Research Center, 6875 Boulevard Lasalle, Verdun, Quebec, Canada, H4H 1R3

Eleven outpatients with Alzheimer disease of moderate severity completed a double-blind placebo-controlled crossover trial of lecithin. Each patient received 10 gm three times daily of a placebo for 3 months. Plasma choline levels rose threefold and remained at that level throughout the lecithin administration period. A significant difference between mean baseline scores and treatment scores was found on tests of new learning ability, indicating a practice effect in there tests. However, there were no differences between mean placebo and lecithin scores on any of the psychological test measures.




This article has been cited by other articles:


Home page
 Am. J. Clin. Nutr.Home page
J. D Fernstrom
Can nutrient supplements modify brain function?
Am. J. Clinical Nutrition, June 1, 2000; 71(6): 1669S - 1673.
[Abstract] [Full Text] [PDF]

Home page
 NEJMHome page
R. Mayeux and M. Sano
Treatment of Alzheimer's Disease
N. Engl. J. Med., November 25, 1999; 341(22): 1670 - 1679.
[Full Text] [PDF]

Home page
 J PsychopharmacolHome page
N.H.P. Allen and A. Burns
The treatment of Alzheimer's disease
J Psychopharmacol, January 1, 1995; 9(1): 43 - 56.
[PDF]

Home page
 Arch NeurolHome page
E. Mohr, J. Schlegel, G. Fabbrini, J. Williams, M. M. Mouradian, U. M. Mann, J. J. Claus, P. Fedio, and T. N. Chase
Clonidine Treatment of Alzheimer's Disease
Arch Neurol, April 1, 1989; 46(4): 376 - 378.
[Abstract] [PDF]

Home page
 Arch NeurolHome page
G. Bruno, E. Mohr, M. Gillespie, P. Fedio, and T. N. Chase
Muscarinic Agonist Therapy of Alzheimer's Disease: A Clinical Trial of RS-86
Arch Neurol, July 1, 1986; 43(7): 659 - 661.
[Abstract] [PDF]

Home page
 ScienceHome page
R. Bartus, R. Dean 3rd, B Beer, and A. Lippa
The cholinergic hypothesis of geriatric memory dysfunction
Science, July 30, 1982; 217(4558): 408 - 414.
[Abstract] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 1981 by AAN Enterprises, Inc.