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© 1981 American Academy of Neurology Mechanisms of confabulationAphasia Research Center and the Department of Neurology, Boston University School of Medicine, the Psychology Service (Ms Shapiro and Dr Gardner), and the Neurology Service (Dr. Alexander). Boston VA Medical Center, Boston. MA, and the Harvard Medical School II)r Mercer). and Harvard Project Zero (Dr. Gardner), Cambridge. MA. Patients who exhibited frank confabulation were examined with four tests designed to elucidate the nature of confabulation in a structured situation, test the ability of confabulators to use cues, and examine the degree to which certain cognitive deficits are associated with confabulation. Two groups of confabulators emerged: mild and severe. Severity of confabulation was associated with perseveration, impaired self-monitoring facility, and failure to inhibit incorrect responses. Attenuation of these cognitive deficits with resolution of confabulation in a single patient suggested that the two levels of confabulation represented different levels of impairment of the same disorder. Address correspondence and reprint requests to Dr. Alexander, Chief, Aphasia Neurobehavior Unit, Boston VA Medical Center, 150 S. Huntington Avenue, Boston. MA 02130. This research was supported in part by the National Institute of Neurological and Communicative Disorders and Stroke. Grant Nos. NS 11408 and NS 06209, and by the Veteran's Administration. Accepted for publication January 20, 1981.
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