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Departments of Neurology, Pathology and Physical Medicine (Drs. Feit, Kirkpatrick, and Pandian), University of Texas Health Science Center at Dallas, and the Department of Neurology (Dr. Van Woert), Mt. Sinai School of Medicine, New York, NY.
Both hypoventilation and myoclonus were suppressed for 4 years with L-5-hydroxytryptophan and carbidopa in a patient with a syndrome of progressive myoclonus, ataxia, central neurogenic hypoventilation, mental retardation, motor neuropathy, and morphologic mitochondrial abnormalities in skeletal muscle.
Address correspondence and reprint requests to Dr. Feit, Department of Neurology, University of Texas Health Science Center, 5323 Harry Hines Blvd., Dallas, TX 75235.
Accepted for publication May 19, 1982
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