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Departments of Medicine (Neurology [Drs. Coffey, Massey, and Mr. Roberts] and Cardiology [Dr. Pryor]), Surgery (Dr. Jones and Mr. Curtis), and Psychiatry (Dr. Coffey), Duke University Medical Center, Durham, NC.
We reviewed 1,669 patients who survived coronary artery bypass graft surgery between 1969 and 1981. A total of 75 cerebral complications were identified, including (1) altered mental state, (2) stroke, and (3) seizure in 64 patients (3.8%). Altered mental state (delirium, hypoxic-metabolic encephalopathy) occurred in 57 (3.4%). Postoperative arrhythmias were associated with an increased risk of altered mental state. Cerebral infarction occurred in 13 (0.8%). Patients who suffered stroke had a higher occurrence of carotid bruits and history of peripheral vascular disease. Seizures occurred in five patients (0.3%). Mortality in patients with a neurologic complication was 29%.
Address correspondence to Dr. Coffey, Departments of Medicine (Neurology) and Psychiatry, Box 31090, Duke Medical Center, Durham, NC 27710.
Presented in part at the thirty-second annual meeting of American Academy of Neurology, Washington, DC, April 1982.
Accepted for publication February 23, 1983.
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