| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
|
|
|
|||||||
|
|||||||||
Neurological Department of Göttingen University, Göttingen, FRG.
The gestational history of 512 women with multiple sclerosis revealed that the risk of MS-onset, exacerbation, or progression was two to three times as high during the 6 months after childbirth as during pregnancy. Using a progression-index as a measure of prognosis (disability divided by duration), the speed of deterioration was comparable for women who became pregnant and those who did not. An apparent but insignificant trend toward better prognosis for women with pregnancies after MS-onset was most likely due to their younger age at onset. The natural course of pregnancy and childbirth was comparable among women pregnant before and during the disease. There was no evidence of an increased frequency of congenital malformations in the offsprings.
Address correspondence and reprint requests to Prof. Sigrid Poser, Department of Neurology, University of Göttingen, Robert-Koch-Str. 40, 3400 Göttingen, FRG.
Supported by the "Deutsche Forschungsgemeinschaft" (Schwerpunkt Ätiologie and Pathogenese der Multiplen Sklerose und verwandter Erkrankungen).
Accepted for publication March 7, 1983.
This article has been cited by other articles:
|
|
 |
|
  M Koch, M Uyttenboogaart, D Heersema, C Steen, and J De Keyser Parity and secondary progression in multiple sclerosis J. Neurol. Neurosurg. Psychiatry, June 1, 2009; 80(6): 676 - 678. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 Y. Chen, H. Lin, and H. Lin Does multiple sclerosis increase risk of adverse pregnancy outcomes? A population-based study Multiple Sclerosis, May 1, 2009; 15(5): 606 - 612. [Abstract] [PDF]
|
|
|
|
|
|
K Gottberg, U Einarsson, C Ytterberg, S Fredrikson, L von Koch, and L W. Holmqvist Use of health care services and satisfaction with care in people with multiple sclerosis in Stockholm County: A population-based study Multiple Sclerosis, August 1, 2008; 14(7): 962 - 971. [Abstract] [PDF]
|
|
|
|
|
|
J. Haas and O. R. Hommes A dose comparison study of IVIG in postpartum relapsing-remitting multiple sclerosis Multiple Sclerosis, August 1, 2007; 13(7): 900 - 908. [Abstract] [PDF]
|
|
|
|
|
|
K Gottberg, U Einarsson, S Fredrikson, L von Koch, and L W Holmqvist A population-based study of depressive symptoms in multiple sclerosis in Stockholm county: association with functioning and sense of coherence J. Neurol. Neurosurg. Psychiatry, January 1, 2007; 78(1): 60 - 65. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 A Parke Drug exposure, pregnancy outcome and fetal and childhood development occurring in the offspring of mothers with systemic lupus erythematosus and other chronic autoimmune diseases Lupus, November 1, 2006; 15(11): 808 - 813. [Abstract] [PDF]
|
|
|
|
 |
|
 U Einarsson, K Gottberg, S Fredrikson, L von Koch, and L W. Holmqvist Activities of daily living and social activities in people with multiple sclerosis in Stockholm County Clinical Rehabilitation, June 1, 2006; 20(6): 543 - 551. [Abstract] [PDF]
|
|
|
|
 |
|
 R. J. Kaaja and I. A. Greer Manifestations of Chronic Disease During Pregnancy JAMA, December 7, 2005; 294(21): 2751 - 2757. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 A R Lorenzi and H L Ford Multiple sclerosis and pregnancy Postgrad. Med. J., August 1, 2002; 78(922): 460 - 464. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 M. A. Hernan, M. J. Hohol, M. J. Olek, D. Spiegelman, and A. Ascherio Oral contraceptives and the incidence of multiple sclerosis Neurology, September 26, 2000; 55(6): 848 - 854. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 C. Confavreux, M. Hutchinson, M. M. Hours, P. Cortinovis-Tourniaire, T. Moreau, and The Pregnancy in Multiple Sclerosis Group Rate of Pregnancy-Related Relapse in Multiple Sclerosis N. Engl. J. Med., July 30, 1998; 339(5): 285 - 291. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
D. C Mohr, D. E Goodkin, N. Gatto, and J. Van Der Wende Depression, coping and level of neurological impairment in multiple sclerosis Multiple Sclerosis, August 1, 1997; 3(4): 254 - 258. [Abstract] [PDF]
|
|
|
|
 |
|
 D. C. Mohr, D. E. Goodkin, W. Likosky, N. Gatto, K. A. Baumann, and R. A. Rudick Treatment of Depression Improves Adherence to Interferon Beta-1b Therapy for Multiple Sclerosis Arch Neurol, May 1, 1997; 54(5): 531 - 533. [Abstract] [PDF]
|
|
|
|
 |
|
 S. Abraham, L. C. Scheinberg, C. R. Smith, and N. G. LaRocca Neurologic Impairment and Disability Status in Outpatients with Multiple Sclerosis Reporting Dysphagia Symptomatology Neurorehabil Neural Repair, January 1, 1997; 11(1): 7 - 13. [Abstract] [PDF]
|
|
|
|
|
|
K. Birk, C. Ford, S. Smeltzer, D. Ryan, R. Miller, and R. A. Rudick The Clinical Course of Multiple Sclerosis During Pregnancy and the Puerperium Arch Neurol, July 1, 1990; 47(7): 738 - 742. [Abstract] [PDF]
|
|
|
|
|
|
K. Birk and R. Rudick Pregnancy and Multiple Sclerosis Arch Neurol, July 1, 1986; 43(7): 719 - 726. [Abstract] [PDF]
|
|
|
|
|
|
S. Poser Arthrogryposis Multiplex Congenita Arch Neurol, January 1, 1986; 43(1): 8 - 9. [Abstract] [PDF]
|
|
| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
