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NEUROLOGY 1983;33:1433
© 1983 American Academy of Neurology

Cerebral palsy—trends in incidence and changes in concurrent neonatal mortality

Rochester, MN, 1950-1976

Tatiana Kudrjavcev, MD, Bruce S. Schoenberg, MD, DrPH, Leonard T. Kurland, MD, DrPH and Robert V. Groover, MD

Neuroepidemiology Section, Office of the Director, Intramural Research Program, National Institute of Neurological and Communicative Disorders and Stroke, National Institutes of Health (Drs. Kudrjavcev and Schoenberg), Bethesda, MD; the Departments of Medical Statistics and Epidemiology (Dr. Kurland) and Neurology (Dr. Groover), Mayo Clinic, Rochester, MN.

We studied all identified cases of cerebral palsy (CP) born to residents of Rochester, MN, during a 27-year period. Incidence rates per 1,000 neonatal survivors were computed for three 9-year intervals. For children with persisting findings, the incidence rate of all syndromes declined from 2.3 to 1.6. For spastic syndromes, this trend was more marked (2.1 to 0.9). For newborns with birthweight over 2,500 g, both CP incidence and neonatal mortality rates (NMR) declined in parallel. For the low birthweight neonate, coincident with a precipitous drop in NMR, the CP incidence rate remained essentially unchanged. In the face of increasing neonatal survival, the overall incidence rate of CP declined. The decrease in the absolute risk of CP was limited to the > 2,500-g neonatal survivor.

Address correspondence and reprint requests to Dr. Kudrjavcev, Neuroepidemiology Section, OD, IRP, NINCDS, NIH; Federal Building, Room 804; 7550 Wisconsin Avenue, Bethesda, MD 20205.

Presented in part at the thirty-third annual meeting of the American Academy of Neurology, Toronto, Ontario, May 1981.

Accepted for publication February 23, 1983.




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