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Attention deficit disorder

Quantitative analysis of CT

Departments of Pediatrics, Neurology, Diagnostic Radiology, and the Yale Child Study Center, Yale University School of Medicine, New Haven, CT.

We compared the measurements of CTs in two groups of children: 35 satisfying DSM III criteria for attention deficit disorder (ADD) and 27 controls with other conditions. The groups were comparable in age, sex, and IQ. Measurements of the anterior horns of the lateral ventricles, bifrontal width, and right and left hemispheres did not differ. The ratio of ventricular size/bifrontal brain width (Evan's Index) averaged 0.237 in ADD and 0.263 in controls—results similar to those obtained in normal children by other investigators. Our findings suggest that when quantitative techniques, contrast populations, and "blind" analysis of CTs are employed, the results are indistinguishable in children with ADD and contrasts. If anatomic abnormalities are present in ADD, they are not discernible with current CT technology.

Address correspondence and reprint requests to Dr. Bennett A. Shaywitz, Yale University School of Medicine, Department of Pediatrics, 333 Cedar Street, New Haven, CT 06510.

Accepted for publication February 23, 1983.

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