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NEUROLOGY 1983;33:1526
© 1983 American Academy of Neurology

Clinical findings in children with occipital spike-wave complexes suppressed by eye-opening

Richard Newton, MRCP and Jean Aicardi, MD

Neurology Unit, INSERM U12, and Clinique de Génétique Médicale.

We studied the EEG abnormality of occipital sharp and slow waves significantly or completely suppressed by eye-opening in 16 patients. All had seizures consisting of transient loss of consciousness. Most experienced additional grand mal, partial (simple or complex), or clonic fits. Response to treatment was poor initially in 9 and subsequently in 11. Learning difficulties were present in 10 children. The cases illustrate the wide range of clinical disorders that may accompany the EEG abnormality and indicate that the prognosis associated with this EEG pattern is not necessarily benign.

Address correspondence and reprint requests to Dr. Aicardi, Hôpital des Enfants Malades, 149 rue de Sèvres, 75743 Paris Cedex 15 France.

Accepted for publication March 10, 1983.




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