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NEUROLOGY 1985;35:31
© 1985 American Academy of Neurology

Prolactin changes after seizures classified by EEG monitoring

Kenneth D. Laxer, MD, John P. Mullooly, PhD and Beth Howell, MD

Department of Clinical Neurophysiology (Drs. Laxer and Howell), Good Samaritan Hospital and Medical Center, and The Health Services Research Center (Dr. Mullooly), Kaiser Permanente Medical Care Program, Portland, OR.

We examined the postictal hyperprolactinemia after seizures classified by EEG and video telemetry. Prolactin did rise after complex partial seizures that involved motor behaviors and was not further increased by secondary generalization. Nontemporal partial seizures or pseudoseizures did not demonstrate this increase. There was no difference in prolactin elevation after generalized tonic-clonic seizures, whether secondarily generalized or generalized from onset. A discriminant function accurately classified 94% of patients with pseudoseizures and 66% of patients with true cerebral seizures for an overall classification accuracy of 72%.

Address correspondence and reprint requests to Dr. Laxer, Good Samaritan Hospital and Medical Center, 1015 NW 22nd Avenue, Portland, OR 97210.

Supported in part by a grant from the Epilepsy Association of Oregon.

Accepted for publication April 13, 1984.




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