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Section of Neurology and Clinical Neurophysiology, University of Liège (Belgium).
Lumbosacral spinal evoked potentials were recorded percutaneously in 22 MS patients with spinal symptoms and in 24 age-matched normal volunteers. Latencies, durations, and areas of waves R and A (level S1) as well as S and P2 (level Th12) were analyzed. The most significant result observed in the MS group was a reduction of the ratio between the areas of P2 and S. The reduction was strongly correlated with intensity of spasticity, but not with other clinical features. The P2/S ratio can thus be proposed as an electrophysiologic measure of spasticity.
Address correspondence and reprint requests to Dr. P. J. Delwaide, Section of Neurology and Clinical Neurophysiology, Hôpital de Bavière, Bd. de la Constitution 66, 4020 Liège, Belgium.
Dr. Schoenen is a Research Associate of the National Fund for Scientific Research (Belgium).
Supported by a grant from the Belgian Research Group on MS and by grant 1.5,60984F of the FNRS (Belgium).
Accepted for publication May 15, 1984.
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