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NEUROLOGY 1985;35:432
© 1985 American Academy of Neurology

Metoclopramide-induced phantom dyskinesia

Joseph Jankovic, MD and J. Peter Glass, MD

Baylor College of Medicine, Texas Medical Center (Dr. Jankovic), and the M.D. Anderson Hospital and the University of Texas Health Science Center, Texas Medical Center (Dr. Glass), Houston, TX.

A 58-year-old woman was receiving chemotherapy for carcinoma of the breast. She was given 1,700 mg metoclopramide IV for 2 months to prevent nausea and vomiting. Within hours after metoclopramide was given, she had hand tremor, akathisia, and truncal and orofacial dyskinesia. These symptoms resolved, but she was left with persistent shoulder stump chorea, the perception of the phantom left arm involuntarily adducted at the shoulder and flexed at the elbow, and dystonic pronation and extension of the hand away from her body. The motor aspects of the phantom dyskinesia will be emphasized.

Address correspondence and reprint requests to Dr. Jankovic, Department of Neurology, Baylor College of Medicine, Texas Medical Center, Houston, TX 77030.

Accepted for publication June 27, 1984.




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