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NEUROLOGY 1985;35:552
© 1985 American Academy of Neurology

Long survival of primary cerebral lymphoma with progressive radiation necrosis

Michael P. Merchut, MD, Catherine Haberland, MD, Mohammad H. Naheedy, MD and Frank A. Rubino, MD

Department of Neurology (Drs. Merchut and Rubino), Hines VA Hospital, Hines, IL, and the Departments of Neuropathology (Dr. Haberland) and Radiology (Dr. Naheedy), Loyola University Medical Center, Stritch School of Medicine, Maywood, IL.

A 56-year-old man lived 8 years after excision and irradiation of a primary cerebral lymphoma. Delayed radiation necrosis caused progressive neurologic deterioration and probably his steroid-responsive episodes of obtundation. Vasogenic edema induced by radiation may account for the latter. An incidental extraneural lymphoma was found postmortem without evidence of CNS lymphoma.

Address correspondence and reprint requests to Dr. Rubino, Department of Neurology, Hines VA Hospital, Hines, IL 60141.

Accepted for publication July 23, 1984.






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