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NEUROLOGY 1985;35:1173
© 1985 American Academy of Neurology

Combined azathioprine and prednisone in chronic inflammatory-demyelinating polyneuropathy

Peter James Dyck, MD, Peter O'Brien, PhD, Carol Swanson, Phillip Low, MD and Jasper Daube, MD

Peripheral Nerve Laboratory, Mayo Medical School and Foundation, Rochester, MN 55905.

Twenty-seven patients with static or worsening chronic inflammatory-demyelinating polyradiculoneuropathy were randomly assigned to alternate day decremental prednisone therapy alone or with azathioprine (2 mg/kg) for 9 months. No statistically significant alterations were demonstrated between these treatment schedules.

Address correspondence and reprint requests to Dr. Dyck, Peripheral Nerve Laboratory, Mayo Medical School and Foundation, Rochester, MN 55905.

Supported in part by a Peripheral Neuropathy Clinical Center Grant from NINCDS (NS14304), a Center Grant from MDA. and Mayo, Borrhard, Upton, and Herrick Funds.

Accepted for publication November 30, 1984.




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