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NEUROLOGY 1985;35:1188
© 1985 American Academy of Neurology

Epileptic amnesic attacks

Benefit from antiepileptic drugs

P. B. Pritchard, III, MD, V. L. Holmstrom, PhD, J. C. Roitzsch, PhD and Joseph Giacinto, BS

Neurology and Psychology Services, VA Medical Center, and the Departments of Neurology and Psychiatry and Behavioral Sciences, Medical University of South Carolina, Charleston, SC.

We studied two sexagenarians who had recurrent circumscribed attacks of amnesia. Their EEGs showed frequent bilateral spikes that arose independently from the temporal lobes, primarily from mesiobasal structures. Amnesic attacks ceased after treatment with antiepileptic drugs. Neuro-psychological tests demonstrated selective cognitive impairments, and short-term memory improved after treatment in one patient. Epileptic amnesic attacks should be distinguished from transient global amnesia, which is clinically similar.

Address correspondence and reprint requests to Dr. Pritchard, Neurology Service, VA Medical Center, 109 Bee Sheet, Charleston, SC 29403.

Presented at the thirty-sixth annual meeting of the American Academy of Neurology, Boston, MA, April 1984.

Accepted for publication November 30, 1984.




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