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NEUROLOGY 1985;35:1223
© 1985 American Academy of Neurology

Tuberous scllerosis with cardiogenic cerebral embolism

Magnetic resonance imaging

Raymond S. Kandt, MD, Stephen S. Gebarski, MD and Mark G. Goetting, MD

Division of Pediatric Neurology, Departments of Pediatrics and Neurology (Drs. Kandt and Goetting), and the Division of Neuroradiology, Department of Fbdiology (Dr. Gebarski), LJniversity of Michigan Hospitals, Ann Arbor, MI.

A girl with tuberous sclerosis and intracardiac masses had at least two episodes of cardiogenic cerebral embolization, the attacks characterized by acute onset of prolonged neurologic dysfunction arising from different vascular distributions in both cerebral hemispheres. Renal embolization was suggested by hematuria. Magnetic resonance imaging (MRI) demonstrated ischemic lesions in cerebral locations predicted by the clinical signs. MRI also demonstrated extensive areas compatible with the dysmyelination of tuberous sclerosis.

Address correspondence and reprint requests to Dr. Kandt, Pediatric Neurology, Duke University Medical Center, Box 3533, Durham, NC 27710.

Accepted for publiration November 14, 1984.




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