HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text (PDF) Correspondence: Submit a response Alert me when this article is cited Alert me when Correspondence are posted Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Carl, G. F. Articles by Hurley, L. S. Search for Related Content PubMed PubMed Citation Articles by Carl, G. F. Articles by Hurley, L. S.

Association of low blood manganese concentrations with epilepsy

Departments of Neurology (Drs. Carl, Gallagher, and Littleton) and Pediatrics (Dr. Flannery), Medical College of Georgia, and the Research Service (Dr. Carl), VA Medical Center, Augusta, GA; and the Department of Nutrition (Drs. Keen, Clegg, and Hurley), University of California. Davis, CA.

A comparison of hospitalized epileptic patients with matched normals showed that the mean whole blood manganese (Mn) G concentration of the epileptic population was significantly lower than the mean of the normal population. The whole blood Mn concentration in the epileptics did not correlate either with seizure frequency or with anticonvulsant therapy. It was observed, however, that patients whose epilepsy was a result of trauma had significantly higher blood Mn concentrations than patients whose history was negative for trauma.

Address correspondence and reprint requests to Dr. Carl, Research Service (151), VA Medical Center, Augusta, GA 30910.

Supported by the Department of Neurology of the Medical College of Georgia, the Department of Nutrition of the University of California at Davis, and the Research Service of the Veterans Administration.

Accepted for publication March 24, 1986.

This article has been cited by other articles:

				A. Z. Kalea, D. A. Schuschke, P. D. Harris, and D. J. Klimis-Zacas Cyclo-Oxygenase Inhibition Restores the Attenuated Vasodilation in Manganese-Deficient Rat Aorta J. Nutr., September 1, 2006; 136(9): 2302 - 2307. [Abstract] [Full Text] [PDF]