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Peripheral neuropathy in systemic vasculitis

Clinical and electrophysiologic study of 22 patients

Service d'Explorations Fonctionnelles, Neurologic (Drs. Bouche, Travers, and Cathala), and the Clinique des Maladies du Système Nerveux (Drs. Léger and Castaigne), Hopital de la Salpetriére, Paris France.

Twenty-two patients with evidence of systemic vasculitis and peripheral neuropathy were clinically and electrophysiologically investigated in a retrospective study. Ten had a polyarteritis nodosa, 6 a probable polyarteritis nodosa, and 6 a Churg-Strauss syndrome. Nine patients presented clinically with mononeuropathy or mononeuropathy multiplex considered typical of ischemic involvement of peripheral nerve; nine had more diffuse neuropathy, two of them a symmetric polyneuropathy. EMG examination revealed more diffuse neuropathy than clinically predicted. Findings were of acute or subacute axonal neuropathy.

Address correspondence and reprint requests to Dr. Bouche, Service d'Explorations Fonctionnelles, Neurologie, Hôpital de la Salpetriére. 47 Bd. de l'Hôpital, 75651, Paris Cedex 13, France.

Accepted for publication March 18, 1986.

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