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NEUROLOGY 1986;36:378
© 1986 American Academy of Neurology

Obsessions and compulsions in Gilles de la Tourette's syndrome

Michael Frankel, MD, Jeffrey L. Cummings, MD, Mary M. Robertson, MD, MRC Psych, Michael R. Trimble, MRCP, FRC Psych, Mary Ann Hill, PhD and D. Frank Benson, MD

Neurobehavior Unit (Drs. Frankel, Cummings, and Benson) and the Department of Research and Development (Dr. Hill), West Los Angeles VAMC (Brentwood Division), and the Reed Neurological Research Center and Department of Neurology (Drs. Frankel, Cummings, and Benson), UCLA School of Medicine, Los Angeles, CA; and the Departments of Psychiatry, Maudsley Hospital (Dr. Robertson) and the National Hospital for Nervous Disease and Institute of Neurology, Queen Square (Dr. Trimble), London, UK.

The incidence of obsessive-compulsive disorder (OCD) in patients with Gilles de la Tourette's syndrome (GTS) was assessed with a specially designed questionnaire. The Inventory was administered to patients with OCD, patients with GTS, and normal controls. Fifty-one percent of the patients with GTS had significantly elevated Inventory scores. The frequent occurrence of OCD in GTS suggests that the two disorders may share common neurobiologic mechanisms.

Address correspondence and reprint requests to Dr. Cummings, Neurobehavior Unit (691/B111), West LA VAMC, 11301 Wilshire Blvd., Los Angeles, CA 90073.

Supported by the Gatepost Foundation, Tourette Syndrome Association, and the Veterans Administration.

Accepted for publication July 2, 1986.




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