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NEUROLOGY 1986;36:432
© 1986 American Academy of Neurology

Familial amyloidosis with cranial neuropathy and corneal lattice dystrophy

Basil T. Darras, MD, Lester S. Adelman, MD, Jesus S. Mora, MD, Richard A. Bodziner, MD and Theodore L. Munsat, MD

Departments of Neurology and Pathology (Neuropathology), New England Medical Center, Tufts University School of Medicine, Boston, MA.

A 64-year-old woman had bilateral facial weakness, mild peripheral neuropathy, incoordination, and impaired balance. A corneal transplant had been performed for corneal lattice dystrophy. Sural nerve biopsy showed mild axonal neuropathy with deposits of amyloid in the perineurium. Histo-chemical studies showed amyloid protein AA in the nerve, but not in cornea or muscle.

Address correspondence and reprint requests to Dr. Munsat, Department of Neurology, Neuromuscular Research Unit, New England Medical Center, 171 Harrison Avenue, Boston, MA 02111.

Accepted for publication July 11, 1985.




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[Abstract] [Full Text]


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