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Childhood dermatomyositis in monozygotic twins

Department of Neurology (Drs. Harati and Niakan), Baylor College of Medicine and Veterans Administration Medical Center, and Departments of Neurology and Pediatrics (Dr. Bergman), The University of Texas Health Science Center, Houston, TX.

Identical twins who developed childhood dermatomyositis 2 weeks apart following upper respiratory infections are reported. Observations suggest that genetic influence on host susceptibility may play a role in childhood dermatomyositis and that a combination of host and environmental factors is most likely necessary to produce the disease.

Address correspondence and reprint requests to Dr. Harati, Department of Neurology, Baylor College of Medicine, 6501 Fannin, Houston, TX 77030.

Accepted for publication September 27, 1985.

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