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Clinical Epilepsy Section (Drs. Theodore, Holmes, and Porter), Medical Neurology Branch, NINCDS; the Diagnostic Radiology Department (Dr. Dorwart), Clinical Center. NIH; and the Section on Neuroimaging (Dr. DiChiro), NINCDS, Bethesda, MD.
We compared the results of x-ray CT, magnetic resonance imaging (MRI), and positron emission tomography (PET) using 18F 2-deoxyglucose in 36 patients with partial seizures. Seventeen patients had localized epileptic discharges on surface EEG. MRI showed an abnormality in 9, CT in 4, and PET in 13 of 14 patients who had the test. Nineteen patients had nonlocalizing EEG discharges. MRI showed an abnormality in 11, CT in 10, and PET in 8 of 12. MRI is more sensitive than CT in detecting structural lesions underlying PET hypometabolism.
Address correspondence and reprint requests to Dr. Theodore, Clinical Epilepsy Section, NIH Building 10, Room 5N-248, Bethesda, MD 20205.
Presented in part at the thirty-seventh annual meeting of the American Academy of Neurology, Dallas, TX, April 1985.
Accepted for publication October 14, 1985.
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