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NEUROLOGY 1986;36:828
© 1986 American Academy of Neurology

Multiple sclerosis

Magnetic resonance imaging, evoked responses, and spinal fluid electrophoresis

Martin R. Farlow, MD, Omkar N. Markand, MD, FRCP(C), Mary K. Edwards, MD, James C. Stevens, MD and Oldrich J. Kolar, MD

Departments of Neurology (Drs. Farlow, Markand, Stevens, and Kolar) and Radiology (Dr. Edwards), Indiana University School of Medicine, Indianapolis, IN.

Magnetic resonance images (MRI), evoked responses (ER), and CSF findings were compared in 39 patients with possible, probable, or definite MS. MRI disclosed multiple lesions (72%) more often than ERs (55%) in the total group of patients. In possible MS, MRI showed multiple lesions in 71%, and ER abnormalities were found in 41%. MRI is the preferred test for patients with suspected MS, but ERs are useful when MRI is normal and in the evaluation of optic nerve or spinal cord lesions.

Address correspondence and reprint requests to Dr. Farlow. Department of Neurology, 125 Emerson Hall, 545 Barnhill Drive, Indiana University School of Medicine, Indianapolis, IN 46223.

Accepted for publication October 22, 1985.




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