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Sporadic Creutzfeldt-Jakob disease in two coworkers

Departments of Neurology (Dr. Leiderman and Choi), Psychiatry (Dr. Decker), and Neuropathology (Dr. Borcich), Stanford University School of Medicine, Stanford, CA.

We report the coincidence of pathologically confirmed sporadic CJD in two unrelated schoolteachers who shared a school wing for 9 months. The first developed ataxia, tremulousness, and dementia 5 months after his last contact with his colleague. Diagnosis of CJD was made 2 months later by brain biopsy. Eight months later, the second teacher developed similar symptoms and died after 9 months. Whether this unique coincidence reflects mere chance or some form of direct viral transmission is unknown. Continued epidemiologic surveillance for any future "coincidences" is warranted.

Address correspondence to Dr. Leiderman, Department of Neurology-C338, Stanford University School of Medicine, Stanford, CA 94305.

Accepted for publication October 10, 1985.

This article has been cited by other articles:

				C. E. M. Hillier and R. L. Salmon Is there evidence for exogenous risk factors in the aetiology and spread of Creutzfeldt-Jakob disease? QJM, September 1, 2000; 93(9): 617 - 631. [Full Text] [PDF]