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Department of Neurology (Dr. Koller and Ms. Cone), Loyola-Hines Medical Center, and the Department of Neurology (Dr. Biary), University of Illinois, Chicago, IL.
We studied 18 patients with essential tremor for difficulty with handwriting, drinking, eating, fine manipulations, and embarrassment. Propranolol and primidone reduced the amplitude of both postural and kinetic tremor. Handwriting, drinking, and eating were improved with therapy, but fine manipulations and motor performance on tapping and pegboard tests were unaltered. Embarrassment remained unchanged. Essential tremor is not a benign condition; disability can be only partly reversed with drug therapy.
Address correspondence and reprint requests to Dr. Koller, Neurology Service (127), Hines VA Hospital, Hines, IL 60141.
Supported by the Veterans Administration.
Accepted for publication November 13, 1985.
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