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Department of Neurology, University of Florida, Gainesville, FL.
Fasciculations and cramps may occur in motor neuron disease or as part of a more benign syndrome. A man with apparently benign fasciculations and cramps for 4 years developed progressive muscle weakness and wasting. Such a previously undocumented evolution of benign fasciculations and cramps to motor neuron disease may further implicate anterior horn cell dysfunction in the pathogenesis of muscle fasciculation-cramp syndromes.
Address correspondence and reprint requests to Dr. Fleet, Department of Neurology, University of Florida, Box J-236, JHMHC, Gainesville, FL 32610.
Accepted for publication October 31, 1985.
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