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NEUROLOGY 1986;36:997
© 1986 American Academy of Neurology

From benign fasciculations and cramps to motor neuron disease

W. Shepherd Fleet, MD and Robert T. Watson, MD

Department of Neurology, University of Florida, Gainesville, FL.

Fasciculations and cramps may occur in motor neuron disease or as part of a more benign syndrome. A man with apparently benign fasciculations and cramps for 4 years developed progressive muscle weakness and wasting. Such a previously undocumented evolution of benign fasciculations and cramps to motor neuron disease may further implicate anterior horn cell dysfunction in the pathogenesis of muscle fasciculation-cramp syndromes.

Address correspondence and reprint requests to Dr. Fleet, Department of Neurology, University of Florida, Box J-236, JHMHC, Gainesville, FL 32610.

Accepted for publication October 31, 1985.




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