HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text (PDF) Correspondence: Submit a response Alert me when this article is cited Alert me when Correspondence are posted Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Montero, C. G. Articles by Martinez, A. J. Search for Related Content PubMed PubMed Citation Articles by Montero, C. G. Articles by Martinez, A. J.

Neuropathology of heart transplantation

23 cases

Department of Cardiothoracic Surgery (Dr. Montero) and Division of Neuropathology (Dr. Martinez). Presbyterian-University Hospital, Pittsburgh, PA.

We reviewed the clinical histories, operative results, and neuropathologic findings of 23 consecutive patients who had heart transplants. Prolonged preoperative hypotension and failure of cerebral autoregulation of blood flow, followed by postoperative elevation of blood pressure beyond the limits of cerebral autoregulation, may account for the high incidence of neurologic complications (70%); 60% were vascular. Immunosuppressive therapy may have been responsible for the high incidence (20%) of opportunistic intracranial infections. Lymphoproliferative disorders occurred in three patients (13%).

Address correspondence and reprint requests to Dr. Martinez, Division of Neuropathology, Presbyterian-University Hospital, DeSoto at O'Hara Streets, Pittsburgh, PA 15213.

Supported in part by a grant from Spanish Insalud of the Ministry of Health, no. 84/6.

Dr. Carlos G. Montero was a recipient of a grant from Fondo de Investigaciones Sanitarias de la Seguridad Social of Spain (FISS).

Accepted for publication January 8, 1986.

This article has been cited by other articles:

				A. Zierer, S. J. Melby, R. K. Voeller, T. J. Guthrie, A. S. Al-Dadah, B. F. Meyers, M. K. Pasque, G. A. Ewald, M. R. Moon, and N. Moazami Significance of Neurologic Complications in the Modern Era of Cardiac Transplantation Ann. Thorac. Surg., May 1, 2007; 83(5): 1684 - 1690. [Abstract] [Full Text] [PDF]

				T. O. Mayer, J. Biller, J. O'Donnell, J. F. Meschia, and D. K. Sokol Contrasting the Neurologic Complications of Cardiac Transplantation in Adults and Children J Child Neurol, March 1, 2002; 17(3): 195 - 199. [Abstract] [PDF]

				W. A. Hall, A. J. Martinez, J. S. Dummer, B. P. Griffith, R. L. Hardesty, H. T. Bahnson, and L. D. Lunsford Central Nervous System Infections in Heart and Heart-Lung Transplant Recipients Arch Neurol, February 1, 1989; 46(2): 173 - 177. [Abstract] [PDF]