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NEUROLOGY 1986;36:1173
© 1986 American Academy of Neurology

Moyamoya pattern of vascular occlusion after radiotherapy for glioma of the optic chiasm

Richard A. Beyer, MD, Maj, MC, Philip Paden, MD, David F. Sobel, MD and Frederick G. Flynn, DO, Maj, MC

Neurology Service, Department of Medicine (Drs. Beyer and Flynn), Letterman Army Medical Center, Presidio of San Francisco, San Francisco, CA; the Department of Ophthalmology (Dr. Paden), Oregon Health Sciences University, Portland, OR; and the Department of Radiology (Dr. Sobel), University of California, San Francisco, CA.

We studied three children who suffered massive strokes 2 to 5 years after intracranial irradiation of optic chiasm gliomas. Arteriography showed moyamoya changes in all three. CTs showed dramatic reduction in tumor size in two patients, but we believe radiotherapy should only be used sparingly to treat optic chiasm gliomas in young children, because its efficacy is unproven, and side effects may be catastrophic.

Address correspondence to Dr. Beyer, Neurology Service, Department of Medicine, Letterman Army Medical Center, Presidio of San Francisco, CA 94129–6700.

Address reprint requests to Technical Publications Editor, Letterman Army Medical Center, Presidio of San Francisco, CA 94129–6700.

Accepted for publication January 28, 1986.




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