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Neurologic outcome and blood glucose levels during out-of-hospital cardiopulmonary resuscitation

School of Medicine, Department of Medicine, Divisions of Neurology and Cardiology, and the School of Public Health and Community Medicine, Department of Biostatistics, University of Washington, Seattle, WA.

We examined the interrelations of outcome, time elapsed during cardiopulmonary resuscitation (CPR), and blood glucose levels drawn from 83 patients with out-of-hospital cardiac arrest. Levels rose significantly during CPR. Although slope and intercept of regression lines differed for those dying in the field and those admitted, regression lines were similar for those who awoke and never awoke after admission. These results suggest that the previously reported association between poor neurologic recovery and high blood glucose level on admission after cardiac arrest is best explained by prolonged CPR, leading to both higher rise of blood glucose and worse neurologic outcome.

Address correspondence and reprint requests to Dr. Longstreth, Division of Neurology, Pacific Medical Center, 1200 12th Avenue South, Seattle, WA 98144.

Supported in part by Grant R18-HS-01943 from the National Center for Health Services Research.

Accepted for publication January 3, 1986.

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